BHRT vs. Traditional HRT: What’s the Difference and Why It Matters
- Breanne Pflanz, APRN-BC
- Oct 4, 2020
- 4 min read
Updated: Oct 28
Hormone therapy has become a widely discussed solution for managing symptoms of menopause, andropause, and other hormone-related imbalances. However, many people are unclear on the differences between traditional hormone replacement therapy (HRT) and bioidentical hormone replacement therapy (BHRT). This confusion can lead to hesitation or the wrong treatment choice. Understanding the key distinctions between BHRT and HRT is essential for making an informed decision about your health.
What Is Traditional Hormone Replacement Therapy (HRT)?
Traditional HRT involves the use of synthetic or animal-derived hormones to supplement declining levels in the body. These hormones are not structurally identical to human hormones and are often derived from sources such as pregnant mare urine (as is the case with Premarin) or manufactured synthetically. Common delivery methods include oral pills, transdermal patches, and intramuscular injections.
Traditional HRT has been widely studied and used for decades. It can be effective in reducing symptoms like hot flashes, night sweats, and vaginal dryness. However, some patients experience side effects such as bloating, mood swings, or an increased risk of blood clots, prompting a search for alternative therapies.
What Is Bioidentical Hormone Replacement Therapy (BHRT)?
BHRT utilizes hormones that are chemically identical to those produced by the human body. These hormones are usually derived from plant sources such as yams and soy and are tailored to each patient’s specific hormone levels through compounding pharmacies.
Unlike traditional HRT, BHRT is customized based on individual lab results and symptoms. This personalization aims to provide better symptom relief with fewer side effects. Common BHRT delivery methods include creams, gels, patches, pills, and pellets inserted under the skin.
Key Differences Between BHRT and HRT
While both therapies aim to restore hormone levels and alleviate symptoms, they differ in several key ways:
Structure: BHRT hormones are bioidentical to those in your body, whereas HRT hormones are structurally similar but not identical.
Customization: BHRT is often personalized based on lab testing, while HRT typically follows a standardized dose.
Source: BHRT is plant-based and compounded; HRT is synthetic or animal-derived and mass-produced.
Monitoring: BHRT usually involves ongoing hormone level testing; HRT may not.
Regulation: Some BHRT formulations are not FDA-approved due to compounding, though the ingredients are FDA-regulated.
BHRT vs. HRT: Which Is Safer?
Safety is a major concern for anyone considering hormone therapy. Studies have shown that both HRT and BHRT can be safe when used under medical supervision. However, individualized dosing and regular monitoring—key features of BHRT—can help reduce risks and side effects.
Many misconceptions exist around BHRT, including the idea that it is completely risk-free. While BHRT is often better tolerated, side effects like bloating, breast tenderness, and mood changes can still occur if not properly managed. Likewise, the risks associated with HRT, such as cardiovascular issues or certain cancers, largely depend on the type of hormones used, dosage, and duration of therapy.
Effectiveness and Patient Outcomes
Both BHRT and HRT are effective at alleviating symptoms of hormone deficiency. However, many patients report higher satisfaction with BHRT due to its individualized approach.
A 2021 study published in Climacteric found that over 75% of women using BHRT experienced significant symptom relief. Adherence rates tend to be higher in BHRT patients, possibly because they feel more involved in their care and see quicker results with fewer side effects.
Who Is a Good Candidate for BHRT or HRT? Ideal candidates for either form of hormone therapy include:
Women experiencing perimenopause or menopause
Men dealing with low testosterone (andropause)
Patients with thyroid or adrenal hormone imbalances
Your medical history, personal preferences, and symptom severity should all factor into your decision. BHRT may be preferable for those seeking a more natural, customized approach, while HRT could be suitable for patients who prefer standardized treatment options.
Why Balanced You Recommends BHRT At Balanced You Medical Wellness, we believe in a personalized approach to hormone health. We recommend BHRT for most patients because of its safety profile, customization, and superior symptom relief.
Our providers use comprehensive lab testing, in-depth consultations, and regular follow-ups to ensure each BHRT plan meets your evolving needs. By choosing BHRT, you're not only treating symptoms—you're investing in long-term wellness and prevention.
FAQs: BHRT vs HRT
Is one more effective?
Both therapies can be effective, but many patients prefer BHRT due to better tolerability and customization.
Are compounded hormones safe? Yes, when prescribed and monitored by experienced providers and dispensed by licensed pharmacies.
Do I need to stop HRT before switching to BHRT?
Not always. Transitions can be made safely under medical supervision.
What’s the cost difference?
BHRT may be slightly more expensive, especially when compounded, but many patients find the benefits worth the investment.
How to Get Started At Balanced You Medical Wellness
The first step is a comprehensive consultation and lab testing. Based on your symptoms and hormone levels, we design a custom BHRT protocol tailored to your unique biology.
Ongoing support includes regular monitoring, dose adjustments, and lifestyle recommendations to help you achieve optimal health.
Final Thoughts:
Understanding the differences between BHRT and traditional HRT is essential for making empowered health decisions. While both therapies have their merits, BHRT’s customized, bioidentical approach often leads to better outcomes with fewer risks.
Take the first step by completing our free online hormone assessment. Ready to take action? Contact Balanced You Medical Wellness today to schedule your consultation.
Sources
Mayo Clinic. (2023). Hormone therapy: Benefits and risks.
North American Menopause Society. (2022). Hormone Therapy Position Statement.
Journal of Clinical Endocrinology & Metabolism. (2022). Custom-compounded BHRT outcomes.
Climacteric. (2021). Patient satisfaction with BHRT.
Endocrine Society. (2021). Overview of hormone replacement options.
Comments